Pure salt and pseudoepherine

I bought 'pure salt' at Trader Joe today to irrigate my nasals. I noted that taking nasal decongestion medicine before the irrigation makes the process easier as the nasal membranes contracted so the saline water could flow better. I will try again later with this pure salt solution.

I found the mechanism of pseudoepherine (nasal decongestion medicine):

the principal mechanism is to cause the release of endogenous norepinephrinevesicles in presynaptic neurons. The displaced noradrenaline is released into the neuronal synapse where it is free to activate the postsynaptic (noradrenaline) from storage adrenergic receptors. These adrenergic receptors are located on the muscles lining the walls of blood vessels. When activated by pseudoephedrine, the muscles contract, causing the blood vessels to constrict (vasoconstriction). The constricted blood vessels now allow less fluid to leave the blood vessels and enter the nose, throat and sinus linings, which results in decreased inflammation of nasal membranes as well as decreased mucus production. Thus, by constriction of blood vessels, mainly those located in the nasal passages, pseudoephedrine causes a decrease in the symptoms of nasal congestion.